Dr. Hrishikesh Pai relies on oocyte cryopreservation via the vitrification technique for improved outcomes.
Oocyte cryopreservation or egg freezing has emerged as a reliable technique to preserve female fertility. When fresh oocyte donation is challenging due to donor unavailability and synchronization, oocytes preserved via the vitrification procedure can be safely and successfully used in IVF cycles.
Dr. Hrishikesh Pai, a leading IVF doctor in India, states, ‘Oocyte cryopreservation offers a solution to fertility preservation for cancer patients or patients who wish to delay their childbirth experience. The advancing oocyte vitrification technology will enable the creation of oocyte banks in the future.’
He adds that oocyte banks can provide quick access to suitable and healthy oocytes and reduce the dependence on the time-consuming synchronization process between donors and patients.
He explains that the latest vitrification technique involves using a high concentration of cryoprotectants to solidify the oocytes without forming ice crystals, which diminishes plasma and membrane integrity. Hence, the advanced vitrification process is preferred for its use of the right concentration and exposure time of cryoprotectants to maintain plasma and membrane integrity.
Vitrification process of oocyte freezing is considered superior to the slow freezing method. Studies reveal that this vitrification process offers better oocyte survival rate, fertilization and embryonic development in vitro as compared to the oocytes preserved via the slow freezing method. Overall, he states that the vitrified oocytes retain their developmental capacity and can be used in IVF cycles with the expectation of successful outcomes. Hence, oocyte preservation via vitrification and its future use can be a viable strategy for people who wish to experience childbirth later.
The reason for the preference for oocyte preservation via vitrification is rapid cooling, wherein the oocytes are rapidly cooled. The use of cryoprotectants ensures no formation of ice crystals and maintains the plasma integrity. The structure of the oocytes is well preserved in their frozen form.
The vitrification process ensures better survival rates despite the freezing and thawing of the preserved oocytes. With no formation of ice crystals, there is less damage to the oocytes, leading to improved outcomes and better pregnancy rates.
The open article named ‘Oocyte Vitrification: A Comparative Analysis Between Fresh and Cryopreserved Oocytes in an Oocyte Donation Program; by Deepa Talreja, Chirag Gupta2,*, Hrishikesh Pai, and Nandita Palshetkar offers valuable insights into the oocyte vitrification process.
The paper also mentions that oocytes preserved through vitrification are on par with the quality of embryos, implantation potential, and pregnancy outcomes of fresh oocyte donations. They concluded that oocyte donation using vitrified oocytes can provide the same quality of embryos, pregnancy, and implantation potential as fresh oocyte donations.
The article also encourages the adoption of the vitrification procedure as a reliable fertility option, especially for those women who wish to preserve their fertility while needing to undergo cytotoxic therapy on account of their malignant health conditions. Moreover, there is no compromise on the quality and the potential of the oocytes preserved through vitrification.
Contact Dr. Hrishikesh Pai
At Lilavati Hospital
A – 791, Bandra Reclamation, Bandra (W), Mumbai – 400 050.
Phone: 91-98200 57722
Email: info@drhrishikeshpai.com
About Dr Hrishikesh Pai
MD, FRCOG (UK-HON), MSc (USA), FCPS, FICOG
Dr Hrishikesh Pai is one of the most eminent gynaecologists and IVF specialists in India. He is credited with introducing IVF and other assisted reproduction techniques in India, and the medical fraternity recognizes him for this.
Immensely talented and versatile gynaecologist Dr. Hrishikesh Pai has been at the forefront of offering infertility treatments in India, introducing many innovative assisted reproduction techniques. He is well recognized globally as a noted authority on IVF treatment and as the 61st president of FOGSI. He is a warm and caring doctor who understands his patients and goes to lengths to solve their infertility issues.
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