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Addictive behaviour such as drug and alcohol abuse may be associated with poor development of the so-called "love hormone" system in our bodies during early childhood, Australian scientists say. The groundbreaking idea has resulted from a review of worldwide research into oxytocin, known as the "love hormone" because of its important role in enhancing social interactions, maternal behaviour and partnership, said researchers at the University of Adelaide. Dr Femke Buisman-Pijlman from the University of Adelaide's School of Medical Sciences, said some people's lack of resilience to addictive behaviours may be linked to poor development of their oxytocin systems. "We know that newborn babies already have levels of oxytocin in their bodies, and this helps to create the all-important bond between a mother and her child," Buisman-Pijlman said in an article in the journal Pharmacology, Biochemistry and Behavior which dealt with the current state of research linking oxytocin and addiction. "But our oxytocin systems aren't fully developed when we're born - they don't finish developing until the age of three, which means our systems are potentially subject to a range of influences both external and internal," Buisman-Pijlman said. "The main factors that affect our oxytocin systems are genetics, gender and environment. You can't change the genes you're born with, but environmental factors play a substantial role in the development of the oxytocin system until our systems are fully developed," Buisman-Pijlman said. "Previous research has shown that there is a high degree of variability in people's oxytocin levels. We're interested in how and why people have such differences in oxytocin, and what we can do about it to have a beneficial impact on people's health and wellbeing," she said. She said studies show that some risk factors for drug addiction already exist at four years of age. "And because the hardware of the oxytocin system finishes developing in our bodies at around age three, this could be a critical window to study. Oxytocin can reduce the pleasure of drugs and feeling of stress, but only if the system develops well," Buisman-Pijlman said. Her theory is that adversity in early life is key to the impaired development of the oxytocin system. "This adversity could take the form of a difficult birth, disturbed bonding or abuse, deprivation, or severe infection, to name just a few factors," Buisman-Pijlman said. "Understanding what occurs with the oxytocin system during the first few years of life could help us to unravel this aspect of addictive behaviour and use that knowledge for treatment and prevention," she said. — PTI
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