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About 8-9 litres of fluid enters the
gastrointestinal tract. This consists of a dietary intake of 2-2-½
litres and the rest is made up of various digestive secretions like
saliva, gastric juices, bile, pancreatic and intestinal secretions.
Normally, most of it is reabsorbed in the small intestine and only a
litre reaches the large intestine (colon), which further absorbs some
water and salts and finally only about 100-300 gm of this is passed out
as faeces. The volume of faeces is more in our population because of the
high fibre intake. It is much lower in the western non-residual diet.
Diarrhoea occurs due to the presence of a poorly absorbable substance in
the lumen of the intestine (osmotic diarrhoea) or some defect in the
cells lining the intestine, resulting in pouring out of the fluids (secretory
diarrhoea) or actual inflammation of small or large intestines (exudative
diarrhoea).
Various descriptive
names are used for different kinds of diarrhoeas. Acute explosive watery
diarrhoea often accompanied by vomiting is referred to as acute
gastroenteritis and is perhaps the commonest cause of infective
acute diarrhoea. There is no accompanying blood or mucus in the stools.
It consists of large amounts of frothy, thin yellowish green fluid. It
is caused by various bacterial, viral and parasitic infections. The
toxins produced by these organisms may be already formed in the food
before it is consumed or it may be produced after they enter the
gastrointestinal track.
Cholera is
a specific form of acute diarrhoeal illness caused by a form of
bacteria, vibrio cholerae, which has played havoc in the gangetic delta
of West Bengal and Bangladesh. It has been responsible for huge
epidemics spreading across West Asia, Africa, Europe and even up to the
USA. With the rapid migration of population across the Indian continent
as well as other parts of the world, cholera is no more limited to its
original geographical limits. In fact, from time to time cholera cases
have been reported in and around Chandigarh, where there is a large
migrant population. Stools in cases of cholera are described as ‘rice
watery’ because of mucus flakes and a large number of cells
floating in the watery stool. The water loss is devastating and a person
can die in a few hours. Some of the readers would recall the havoc it
played among the refugees during the 1971 Bangladesh war.
Acute infective
diarrhoea may take the form of dysentry which is characterised by
frequent but relatively small volume of stools containing blood and
mucus, accompanied by cramps and signs of inflammation like fever and
toxaemia. The best known examples of dysentry are amoebic dysentry
caused by amoeba and a group of bacteria discovered by Japanese
bacteriologist Shiga in 1897 and referred to as shigellosis.
Although diarrhoea is
not the main feature in typhoid fever but in its basic epidemiology and
causation, typhoid fever is very akin to this group of diseases with the
difference that the bacteria causing typhoid (salmonella typhi) lodges
itself in the wall of the intestine and enters the blood, causing severe
toxicemia and high fever.
Traveller’s diarrhoea
is one of the very common diarrhoeal illnesses. It was referred to by
various colourful names like ‘hill diarrhoea of Shimla,’ ‘Mexican
belley’ and I am tempted to coin another name, the ‘Shatabadi
Express tummy’ considering the number of people who develop this
ailment after travelling on the train. The cause of traveller’s
diarrhoea is unclean water and food during travel, specially in the
tropical parts of the world, including South East Asia, Mexico and
African countries.
Although any form of
bacterial, viral or parasitic infection can be responsible for traveller’s
diarrhoea, depending upon the prevalence of an organism in the area of
travel, but a bacteria, e.coli, has now been found to be the commonest
cause of this type of diarrhoea. This bacteria is a normal habitant of
the intestine but certain strains of this can cause devastating
diarrhoea.
Prevention and treatment
The secret of
management of infective diarrhoea lies in prevention by good public
health measures, supply of clean drinking water and health education
among the masses. It cannot be overemphasised that a lot of
responsibility lies with the village panchayats, municipalities, public
health departments of the state and the Central Governments to make
every effort for the provision of safe drinking water.
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At the personal and
family levels. water can be filtered, boiled or exposed to
sophisticated equipment using ultravoilet rays.
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Food handlers in
all hospitals, restaurants and caterers should be closely screened
and supervised.
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Cut fruits,
unwashed fruits, vegetables, salads and articles containing green
leaves are better avoided.
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In hot weather,
leftover foods should be avoided and no stored in the refrigerator
for more than 6-8 hours as bacteria do start growing after some
time.
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While travelling
one should take precautions and avoid exposed raw fruits, cold
snacks of any kind, unbottled drinks and any thing does not appear
to be clean. Even bottled mineral water has been found to be unsafe
in Chandigarh itself as the plants preparing it do not meet the
standards.In case of children extra precaution is required. It is
much safer to breast feed the child for at least 6-9 months and feed
with simple spoon, cup or glass later.
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Washing hands
before eating anything and keeping the eating area clean are a must.
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The Public Health
Department should carry out frequent checks at all levels of public
catering, including rehri markets or dhabas.
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For travelling into
the endemic areas, cholera vaccine and other available vaccines
should be used for prevention.
- Since diarrhoeal diseases can kill
by loss of water and salt, even before reaching a doctor or
hospital, salt and fluid should be replaced with oral rehydration
salts (ORS). These can be prepared by putting a little sugar, salt
and baking soda in boiled water. Rice water and coconut water are
other simple substitutes which can prevent initial dehydration.
Causes of
infective diarrhoea
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Basically it
is lack of clean water (water borne) or food, poor personal
hygiene of the persons serving or eating food (faeco oral
route). Lack of clean water is the single most factor in the
world for the cause of infective diarrhoeas. According to WHO
estimates about 60 per cent of the world population does not
have access to clean drinking water. In our country, clean
drinking water is still not available to about 40 per cent of
the population.
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With all
other being equal, the hot and humid climate of the tropics
does promote growth of all kinds of organisms causing
diarrhoea.
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Inadequate
sewerage disposal and lack of environmental hygiene in
general.
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Rapid
urbanisation without adequate provision of infrastructure and
healthcare.
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Uncooked,
poorly cooked and badly handled unrefrigerated food.
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Eating out
while travelling or at picnics, banquets, large gatherings
like religious congregations (remember the Kumbh Mela
outbreaks), day-care centres for infants, prisons, war camps
and fast food restaurants.
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Paradoxically,
hospitals, sanitoriums and mental health institutions are very
prone to these infections.
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Poor immunity
resulting from malnutrition, drug abuse and of course AIDS.
- Unusual sex habits predispose
one to certain infections.
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